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Wherever you are in your drug discovery or development pipeline, we help you turn spatial and multimodal data into clear, reproducible insights. Every solution in Weave helps you move from raw spatial data to clear biological interpretation, with standardized workflows you can reuse across cohorts and programs.

Weave® solutions that move your drug programs forward

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Identify and confirm biological in spatial tissue context

Your challenge

Early discovery and validation depend on identifying real biological mechanisms and confirming they hold up across tissues and cohorts. Cellular behavior is shaped by tissue structure, spatial relationships, and cellular neighborhoods. Spatial context is the key to interpreting early signals and validating them with confidence.

What you can do with Weave

Weave brings your spatial, molecular, and annotation data together so you can detect early biological patterns and validate them before committing to costly downstream work.

Identify spatial signatures linked to disease biology

Detect cellular neighborhoods and microenvironments driving phenotype

Increase confidence in findings through orthogonal, spatial multi-omics confirmation

Compare hypotheses across cohorts with reproducible workflows

Build structured, AI-ready datasets that accelerate downstream validation

Publications & Presentations

Weave-powered studies have revealed multicellular mechanisms in oncology, fibrosis, and neurobiology. Check out the resources below for more information.

Explain how interventions reshape tissue biology

Your challenge

You need to connect phenotype to mechanisms and understand how interventions reshape local tissue environments. Without spatial context, pathway shifts and cell-state transitions are hard to interpret, making mechanism-of-action claims difficult to defend.

What you can do with Weave

Weave makes it easy to compare treated vs. control samples, map pathway changes, and see how cell-cell interactions and microenvironments shift.

Localize drug delivery down to the cellular level

Link molecular change to spatial structure

Map ligand–receptor communication and pathway activity

Quantify shifts in cell states and local microenvironments at multiple time points

Validate mechanisms with multimodal, spatially resolved evidence

Reduce ambiguity in MoA claims by linking pathway activity to precise tissue microenvironments

Related publications

Weave supports multi-modality alignment in top-20 pharma preclinical programs and has enabled co-registration of MSI, spatial transcriptomics, spatial proteomics, IHC, and reference atlases.

Track your drug and the responses it drives

Quantify compound localization and kinetics in spatial context

Quantify drug exposure, link it to pathway or cell-state changes, and compare across cohorts to measure drug distribution where it matters: inside tissue architecture. Understanding where a compound actually accumulates, and which cell states it influences, helps explain exposure–response relationships that bulk assays miss.

Weave maps compound exposure with molecular outcomes

Unifying MSI, IF, transcriptomics, and histology with QC and spatial alignment ensures multi-assay comparisons remain reproducible across batches and instruments.

The benefits of Weave

Localize drug delivery down to the cellular level and link to phenotypic impact

Spatially quantify exposure-response relationships at different time points

Compare treated and control cohorts at scale

Co-register MSI with proteomics and transcriptomics for deeper insights

Reduce manual reprocessing with automated harmonization

Related publications

Validated MSI co-registration projects demonstrate Weave’s ability to align modalities with radically different spatial resolutions.

Clinical Research & Stratification

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Compare spatial biomarkers to guide multi-site clinical programs

Stratify patients based on spatial biomarkers and tissue-level phenotypes. Reproducible harmonization across sites offers clear insights into which signatures drive outcomes. Harmonized spatial data helps you compare biomarkers across sites, timepoints, and assays, making patient stratification and signature validation more reliable.

Weave® integrates MSI, histology, and spatial omics for PK/PD

Enabling comparison of biomarker expression, tissue architecture, and spatial signatures that correlate with outcome or response.

The benefits of Weave

Identify spatial and/or molecular biomarkers linked to patient outcome

Compare tissue signatures across sites and timepoints

Reuse harmonized datasets for downstream modeling

Maintain regulatory-grade provenance and lineage

Related publications

Weave-powered studies have revealed multicellular mechanisms in oncology, fibrosis, and neurobiology. Check out the resources below for more information.

Move from isolated assays to reproducible spatial insights

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